Do you consider sugar substitutes to be a safer alternative to sugar? Think again. Recent studies have shown that a common artificial sweetener used in dietary carbonated drinks and other zero confectionery food products can actually increase the risk of heart attacks and strokes.
In the last test Metabolism published in the Cellism journal, scientists evaluated mice fed with aspartame, a common substitute for sugar, for 12 weeks and compared them with mice without a diet set by the sweetener. The amount of aspartame consumed mice (daily doses of food containing 0.15%) were equivalent to three cans of diet soda per day for people.
The results revealed that aspartame feeded mice had increased inflammation and “larger and more fatty tiles” in their arteries, two main factors that can increase the risk of cardiovascular disease.
Scientists also noticed that the blood of the mice had a sharp growth of insulin after Aspartame entered their system. Then they determined that elevated insulin levels could be a key link between aspartame and cardiovascular health.
“Aspartame triggers an elevated level of insulin in animals, which in turn contributes to atherosclerosis – fatty platelets in the arteries, which can lead to a higher level of inflammation and an increased risk of heart attacks and stroke in time,” noted the scientists of Wa press release.
The study identifies a specific immune signal, CX3CL1, which is activated when stimulating insulin as a key factor of inflammation and collection of plaque.
“Because the blood flow through the artery is strong and solid, most chemicals will be quickly washed when the heart pumps. Unexpectedly, not CX3Cl1. It remains glued to the surface of the internal lining of blood vessels. There it works like lures, catching immune cells when they pass – said the elder author of Yihai Cao.
CAO believes that the same immune signal, CX3CL1, can be a potential goal of treating other chronic diseases that include blood vessels such as stroke, arthritis and diabetes. Developing means that block the functions of this immune signal can provide a new way of treating and preventing ordinary and deadly diseases in humans.
“Artificial sweeteners have penetrated almost all kinds of food, so we need to know the long-term impact on health,” Cao struck.