People who receive a vaccine for shingles have a 23% lower risk of cardiovascular events, including stroke, heart failure and coronary artery disease, according to the study of over a million people published in today’s (Tuesday).
The protective effect of the vaccine lasts up to eight years and is particularly clear for men, people under the age of 60 and people with an unhealthy lifestyle, such as smoking, drinking alcohol and being inactive.
The study was conducted by Professor Dong Keon Yon from Kyung Hee University College of Medicine, Seul, and South Korea.
Shielding causes a painful rash and can lead to serious complications, especially in older adults and people with a weak immune system. Previous studies show that without vaccination about 30% of people can develop half -pass during their lives.
In addition to rashes, shingles are associated with a higher risk of heart problems, so we wanted to find out if vaccination could reduce this risk. “
Professor Dong Keon Yon, Kyung Hee University College of Medicine, Seul, South Korea
The study included 1,271,922 people aged 50 or older people living in South Korea. Researchers have collected data since 2012, whether people received a shingle vaccine and combined it with data on their cardiovascular health and data on other factors that can affect health such as age, gender, wealth and lifestyle.
The vaccine was a vaccine of the living, which means that it contained a weakened form of chickenpox virus that causes shingles. In many countries, this type of vaccine is currently being replaced by a non-mixing, recombinant vaccine, which means that it contains protein from chickenpox virus.
The study showed that among the people who received the vaccine, there was a generally 23% lower risk of cardiovascular events, at a 26% lower risk of serious cardiovascular events (stroke, heart attack or death due to heart disease), 26% lower risk of heart failure and 22% lower risk of coronary artery disease.
The protective effect was the strongest within two to three years after the administer of the semi -forest vaccine, but scientists discovered that the protection lasted up to eight years.
Professor Yon said: “Our study suggests that a shelf vaccine can help reduce the risk of heart disease, even in people without known risk factors. This means that vaccinations can offer health benefits except for the semi -aim.
“There are several reasons why a shelf vaccine can help reduce heart disease. Half -based infection can cause damage to blood vessels, inflammation And creating clots that can lead to heart disease. By preventing shingles, vaccination can reduce this risk. Our study showed stronger benefits in younger people, probably due to a better immune response and men, probably because of the differences in the effectiveness of the vaccine.
“This is one of the largest and most comprehensive research after a healthy general population for a period of up to 12 years. For the first time it allowed us to examine the relationship between semi -gray vaccinations and 18 different types of cardiovascular diseases. We were able to take into account various other health conditions, lifestyle factors and social and economic status, thanks to which our results are more reliable.
“However, because this study is based on the Asian group, the results may not apply to all populations. Because the live vaccine is not suitable for everyone, further research should be taken into account on the recombinant vaccine.”
Professor Yon and his colleagues also plan to examine the impact of a recombinant vaccine to see if he has similar benefits from limiting heart disease.
Source:
Reference to the journal:
Lee, S., (2025). LIVE STRONG VALIDAY AND CERTIVITIES: Nationwide, South Korean study. . doi.org/10.1093/eurheart/ehaf230.