Can turmeric/curcumin help in diabetes weight control?

In the last study published in the journal Scientists assessed the impact of curcumin supplementation or turmeric on anthropometric indicators in People with type 2 diabetes Mellitus (T2DM) or Prediabetes. Diabetes imposes a significant social burden, including indirect and direct consequences, such as losses related to work and reduced performance.

The International Diabetic Federation estimates that diabetes costs will reach $ 1.03 trillion by 2030. Due to the disadvantages of conventional treatments, such as dosage tolerance, side effects and high costs, new, profitable and safe alternatives are studied.

Herbal supplements are widely used for medicinal purposes. Turmeric is widely used as a culinary additive to increase taste and color. He deals with the most common dietary supplements around the world. However, its therapeutic effectiveness is limited due to low bioavailability. This caused interest in advanced delivery methods, such as nanoparticles and coexisting administration with piperine, to improve absorption.

Kurcumin, the main active ingredient in turmeric, has a beneficial effect on glucose and anthropometric indicators in metabolic diseases. Reduces the expression of transcription factors involved in the production of fat in the liver. In addition, curcumin exerts anti -obesity by repressing the differentiation of preadipocytes and inhibiting mitogenesis. It can also increase fat burning, reduce fat accumulation and increase energy expenditure.

About the study

In this study, scientists systematically exercised and analyzed randomized controlled tests testing curcumin or turmeric in people with T2DM or Prediabetes. Attempts were taken into account if they measured body weight, waist size, fat mass or other body composition indicators and compared placebo results. Research on pregnant women or combining curcumin with other treatments has been excluded. The study conducted international guidelines for systematic inspections and assessed the strength of evidence using the assessment system.

Arrangements

Scientists reviewed 20 eligible research involving 1387 adults. The most commonly used turmeric/curcumin doses from 80 to 2100 mg per day.

In people with T2DM, supplementation led to a small but statistically significant reduction in body weight, the size of the waist, the percentage of fat and the hip circuit. However, this did not clearly affect the ratio of BMI or the waist to the hips, and the certainty of evidence for most of the results was low or very low.

In pre -diabetes, turmeric/curcumin reduced the body weight and the size of the waist, but not BMI, and the evidence was uncertain.

People who took curcumin forms with high absorption or used it for at least 12 weeks, usually saw greater benefits.

Only a few studies reported side effects that were generally mild and included stomach discomfort, itching or nausea.

In particular, the study also showed that longer use (over 22 weeks) was associated with weight reduction, and higher doses (about 1500 mg/day) were associated with smaller waist.

Conclusions

This study suggests that turmeric/curcumin supplements can help reduce some obesity markers, especially body and waist perimeter, in people with pre -laster and T2DM. Encouraging, these effects were small and often based on evidence assessed as low.

The strongest results appeared when high absorption preparations were used in more longer periods. More stringent studies are needed to confirm these effects and understand which types of patients bring the most.