Low sperm quality associated with shorter life

In the last published study, scientists determine how low sperm quality can affect the risk of mortality.

How does men infertility affect mortality?

In addition to direct impact on reproduction, men’s infertility may also reflect the individual’s susceptibility to some diseases and premature mortality. In fact, several studies have been recorded in the dose -dependent relationship between semen quality and health impairment, as well as semen concentration and risk of mortality.

Although most men who are looking for reproductive counseling are young and their chronic health conditions have been less often diagnosed, infertile men often have more co -existing than comparable fertile men. Despite these observations, it is not clear how the presence of existing health problems before assessing the quality of semen affects the potential relationship between men’s infertility and mortality.

About the study

The current study included 78 2,284 middle -aged men who underwent screening in the quality of sperm due to infertility of the steam. All semen analyzes were carried out at the Public Laboratory in 1965–2015 in Copenhagen, Denmark. Mortality data was collected from national registers by the median 23 years, with the longest observation period is 50 years.

The expected life expectancy and experience differences were calculated between groups and stratified according to the quality of semen. In the subgroup with later results obtained in 1987–2015, the status of education and diseases was also noted to enable the analysis of taking into account the impact of these factors on patients’ results.

Research results

Among the group of the median, the semen concentration was 51 million/ml in men with diagnosed disease during testing compared to 47 million/ml in healthy men. The lower median numbers of sperm were more often reported to people with cancer, cardiovascular diseases and breeding disease diseases.

8,600 deaths were reported throughout the observation period, which reflected 11% of the study. The dose -dependent relationship between the speed of survival and the reducing sperm quality was observed. All semen parameters showed the same pattern, even after adapting to the education and presence of diseases at the time of the exam.

Men with a total busy number of sperm (TMSC) of 120 million or more life (LE) (LE) about 80.3 years. For comparison, men with azoospermia, which are defined as TMSC with zero, have experienced a reduction in life expectancy by 2.7 years to an average of 77.6 years. Men with Azoospermia also had a 39% increased risk of death compared to fertile men.

Men from TMSC from scratch to five million were 78 years old. The risk of death was 61% higher in men from TMSC from five to 10 million, which makes these people with the greatest risk of mortality.

In obstructive azoospermia, the man is healthy and the production of semen is normal; However, semen cells cannot be released to the semen due to the blockade. In a non -azoospermia, the production of semen is very low or absent, which indicates the disease underlying the disease. The current study did not differ between people with obstructive or non -structural azoospermia.

The risk of mortality was 38%, 27% and 16% higher for people with sperm number between 10-40, 40-80 and 80-120 million, respectively. Compared to healthy men, men with previously existing diseases had a greater risk of mortality in each layer, which indicates that the activity of the disease was already severe.

Implications

Some men with low quality semen are more likely to die for any reason in a relatively earlier age. In the current study, the reduced semen quality parameters, even if the threshold of male infertility, led to lower survival indicators.

Previous studies suggest that a decrease in health is associated with impaired sperm quality. Therefore, compared to healthy men, survival results are reduced for infertile men who have already been diagnosed with one or more diseases.

. “

Conclusions

Lower semen quality predicted a shorter life, with this connection is consistent for all sperm parameters. It was found that men with high quality sperm live 2.7 years longer compared to men with the lowest quality semen.

There was no difference in the results of patients after considering the educational status and previously existing disease states. Therefore, additional tests are needed to verify these findings and accurately finds what diseases are associated with lower sperm quality.

Future research should also identify endangered populations with greater specificity to support the development of preventive programs.