Endometriosis increases the risk of premature menopause in women

Women suffering from endometriosis have an increased risk of premature and early menopause, both naturally and surgically, scientists from the University of Queensland said.

A comprehensive international study has shown that women with endometriosis are at a 7x risk of surgical menopause (including the removal of both ovaries) and have a greater risk of premature menopause (40 years ago) or early menopause (aged 40-44).

Dr. Hsin-Fang Chung, from UQ’s School of Public HealthIN He said that although it is known that endometriosis and its treatment can reduce the quality and quantity of egg, testing its effect on Menopause time He was limited.

We discovered that surgical menopause occurred on average 19 months earlier in women with endometriosis, while the natural menopause took place 5 months earlier.

Women with endometriosis are twice as vulnerable to surgical menopause under the age of 40, i.e. 1.4 times more exposed to natural menopause before 40. ”

Dr. Hsin-Fang Chung, UQ’s School of Public Health

Elderly author, Professor Gita Mishra, said that she was already known early, and surgical menopause was associated with adverse results such as cardiovascular diseases and premature death.

“Prevention of early or medical menopause requires a comprehensive understanding of its causes and proactive means to solve the long-term health threats related to it,” said Professor Mishra.

The study – which analyzed data from almost 280,000 women in Australia, Great Britain, Sweden and Japan in 1996–2022 – is the largest to examine the type and date of menopause in women with endometriosis.

The test is part Interlace, international cooperation examining women’s reproductive health and chronic diseases throughout their lives.

Endometriosis is chronic and often devastating inflammatory disease, affecting 1 in 7 Australian women, where tissue similar to the lining of the uterus grows in other parts of the body.

Dr. Chung said that he hopes that evidence would inform about updates of guidelines regarding endometriosis management, emphasizing the importance of long -term monitoring of this state.

“Women with endometriosis should be aware that they can be exposed to an increased risk of early or induced menopause, regularly visit a family doctor to check the risk factors of a chronic disease and focus on prevention strategies,” she said.

The next step of Dr. Chung is to examine the effect of endometriosis on the long -term risk of chronic disease.

The discoveries will be presented at the 16th World Congress for Endometriosis in Sydney this month.

. Research is published in Human reproduction.