The examination reveals complex load and survival patterns among people with digestive cancers in China

The examination reveals complex load and survival patterns among people with digestive cancers in China

Cancer cancers of the digestive system (DSMTS), including esophagus, stomach, colorectal, liver and pancreas-breaking tumors-breaking the serious challenge of public health in China. A recent national epidemiological study conducted by HU Published in Trends in 2004–2021 were analyzed, revealing complex load and survival patterns. While progress has been made in reducing mortality from some cancers, the general impact remains significant, with attention -noted differences in demographic and geographical lines. Below are key arrangements:

Decreasing mortality from the main page DSMTS

Standardized age of mortality rates (ASMR) of esophagus, stomach and liver cancer dropped significantly over 18 years: (i) esophageal cancer: ASMR fell with an average annual percentage change (AAPC) of -4.30%; (ii) stomach cancer: ASMR decreased at AAPC -4.14%; (iii) Liver cancer: ASMR has fallen from AAPC -2.58%. These improvements are attributed to increased public health policy, early screening programs, better control of risk factors such as Helicobacter pylori () and hepatitis B and socio -economic development.

Growing load of colorectal tumors and pancreas

On the other hand, colorectal and pancreatic cancers showed disturbing growth: (i) colorectal cancer: severity increased from AAPC by 3.59%; (ii) pancreatic cancer: both rawness and standard age increased, with AAPC by 5.72% and 2.71%, respectively. These increases are partly associated with diets from Western, increased alcohol consumption, sitting lifestyle and late stage diagnosis.

Life expectancy and improved life expectancy (goals)

In the years 2004–2021 the average life expectancy in China increased by 4.4 years. Importantly, when deaths due to DSMT have been hypothetically eliminated, life expectancy (goals) will increase by 4.06 years, emphasizing the significant impact of these cancers on health. Profits were more clear in rural areas and among men, which suggests improving health capital, but also emphasizing the areas where further efforts are needed.

Sex, geographical and socio -economic differences

The men had a consistently higher premature mortalityPotential years of life (pyll) and mortality from the age of DSMT compared to women: (i) total pyll: 16.3 million people for men vs. 5.4 million for women; (ii) average years of life (Ayll): 14.64 years for men vs. 13.52 years for women. These gaps reflect higher smoking and alcohol consumption among men and delayed health search behavior.

Rural residents wore a disproportionate burden: (i) rural areas constituted 15.1 million pyll, more than twice as large as in urban areas (6.6 million); (ii) ASMR pancreatic cancer was created steeply in rural areas (AAPC = 4.62%). Limited access to high -quality healthcare and subsequent diagnoses contribute to these results.

Cancer weight varies significantly depending on the region: (i) Eastern regions showed a significant reduction in esophageal, stomach and liver cancer; (ii) Western regions, while improving, had higher Ayll values, indicating later diagnosis and worse access to treatment; (iii) pancreas and colorectal crayfish increased rapidly in Western and middle regions.

Contributing factors

(AND) Screening and early detection: The government improved by the government has improved the early diagnosis since 2005. Targeted programs in areas with a high accident, including in the Haihe and Anyang river basin, were particularly effective in the case of esophageal cancer. (II) Vaccinations and risk control: The introduction of a vaccine against hepatitis B to the Chinese national vaccination program in 2002 played a key role in reducing the liver cancer indicator. Other improvements include better food safety, reduced aflatoxine and common exposure liquidation. (III) Lifestyle westernization: As the economic conditions improved, diet patterns moved towards high fat and low fiber with increased meat consumption. These changes are associated with the growing frequency of colorectal cancer and pancreas. A sedentary lifestyle, obesity, smoking and alcohol abuse further worsen the risk, especially in younger populations. (IV) Diagnostic progress: Progress in imaging technologies-CT, MRI and nuclear magnetic resonance imaging improved the detection of pancreatic cancer, although the late presentation remains common.

To sum up, although progress has been made in reducing mortality from several main digestive cancers, the growing load of colorectal and pancreatic cancer, especially among rural and male populations, signals the change in Chinese cancer epidemiology. Future efforts must focus on health capital, primary prevention and early detection to maintain and expand the last benefits in life expectancy. As China is progressing for the purposes of the “Healthy China 2030” initiative, comprehensive cancer control remains the foundation stone of public health development.

Source:

Reference to the journal:

Hu, T. ,. (2025) Error of digestive cancers and its impact on life expectancy in China, 2004–2021. doi.org/10.1136/egastro-2024-100148.

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