Tag Archives: breast

Survivor breast cancer faces accelerated aging associated with tumors and treatment

Survivor breast cancer faces accelerated aging associated with tumors and treatment

Many people who have survived breast cancer (BC) experience accelerated aging, potentially because of cancer itself or the effects of various treatment methods. Last study in He examined the relationship between phenotypical acceleration of age (PAA) and the features and treatment of BC. Entry Breast cancer is the most common cancer Among women around the […]

T-DM1 reduces the long-term risk of death in patients with HER2-positive breast cancer

T-DM1 reduces the long-term risk of death in patients with HER2-positive breast cancer

In patients with high-risk HER2-positive breast cancer after surgery or adjuvant therapy, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared with trastuzumab alone, according to final trial results KATHERINE phase III clinical trial conducted by scientists from the University of Pittsburgh and UPMC […]

Spatial transcriptomics uncovers new treatment pathways for triple-negative breast cancer

Spatial transcriptomics uncovers new treatment pathways for triple-negative breast cancer

In a recent study published in the journal researchers are analyzing tumor architecture, cell composition, and the microenvironment in patients with triple-negative breast cancer (TNBC) using spatial transcriptomics and histomorphological analysis. A total of nine TNBC spatial archetypes were identified and associated with disease outcomes and actionable characteristics, as well as a tertiary lymphatic gene […]