In patients with high-risk HER2-positive breast cancer after surgery or adjuvant therapy, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared with trastuzumab alone, according to final trial results KATHERINE phase III clinical trial conducted by scientists from the University of Pittsburgh and UPMC […]
Scientists from POSTECH and Kyungpook National University have developed a novel inhalation drug delivery system for lung cancer using mucoadhesive protein nanoparticles inspired by the adhesive properties of marine mussels. This work was initiated by Professor Hyung Joon Cha (Department of Chemical Engineering and Graduate School of Convergence Science and Technology with specialization in Medical […]
A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center shows that many cases of high-risk, non-metastatic, hormone-dependent prostate cancer may be more advanced than previously thought. The study, published in , found that almost half of high-risk prostate cancer patients previously classified as non-metastatic on conventional imaging actually have metastatic […]
According to the World Health Organization, in 2022 alone, over 20 million people will be diagnosed with cancer and almost 10 million will die from it. Although the scope of cancer is vast, the answer to more effective treatments may lie in a microscopic cell. A paper published by the Lele Lab, led by Texas […]
In a recent study published in the journal researchers are analyzing tumor architecture, cell composition, and the microenvironment in patients with triple-negative breast cancer (TNBC) using spatial transcriptomics and histomorphological analysis. A total of nine TNBC spatial archetypes were identified and associated with disease outcomes and actionable characteristics, as well as a tertiary lymphatic gene […]