Tag Archives: proteins

Umbilical cord proteins help detect early sepsis in premature babies

Umbilical cord proteins help detect early sepsis in premature babies

Scientists from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago and colleagues identified several proteins from the blood of the umbilical blood of premature newborns, which signal acute systemic inflammation as a response to infection, ensuring objective and non -invasive diagnosis of early sepsis. This discovery can be […]

The new approach can prevent neurotoxic proteins in ALS

The new approach can prevent neurotoxic proteins in ALS

Scientists from Goethe University, Johannes Gutenberg University Mainz and Kiel University discover a possible method of preventing protein aggregates – the Cluster4future Proxidrugs research project. If the TDP-43 protein is defective inside the nerve cell, it can create neurotoxic aggregates that cause a neurodegenerative lateral nitrogenic sclerosis (ALS). Nerve cells are also damaged by TDP-43 […]

Generation of mutant proteins via adversarial attacks on the AlphaFold2 model

Generation of mutant proteins via adversarial attacks on the AlphaFold2 model

Announcement of a new publication in the magazine. Proteins are essential macromolecules that perform functions according to their conformational dynamics. The study of conformational changes induced by protein mutations is a standard approach used to understand the underlying mechanisms mutation-related physiological and pathological processes. To increase the efficiency and reduce the cost of biological experiments, […]