Scientists from Goethe University, Johannes Gutenberg University Mainz and Kiel University discover a possible method of preventing protein aggregates – the Cluster4future Proxidrugs research project. If the TDP-43 protein is defective inside the nerve cell, it can create neurotoxic aggregates that cause a neurodegenerative lateral nitrogenic sclerosis (ALS). Nerve cells are also damaged by TDP-43 […]
Announcement of a new publication in the magazine. Proteins are essential macromolecules that perform functions according to their conformational dynamics. The study of conformational changes induced by protein mutations is a standard approach used to understand the underlying mechanisms mutation-related physiological and pathological processes. To increase the efficiency and reduce the cost of biological experiments, […]