Tag Archives: reduces

DDR2 increases BMP-dependent bone regeneration and reduces heterotopic ossification

DDR2 increases BMP-dependent bone regeneration and reduces heterotopic ossification

Research into bone regeneration has taken a significant step forward with the discovery of a key mechanism that could transform treatments for bone diseases. Scientists have identified how discoidin domain receptor 2 (DDR2) enhances bone morphogenetic protein (BMP)-dependent bone regeneration while reducing the risk of heterotopic ossification (HO), offering promising therapeutic opportunities. This breakthrough sheds […]

T-DM1 reduces the long-term risk of death in patients with HER2-positive breast cancer

T-DM1 reduces the long-term risk of death in patients with HER2-positive breast cancer

In patients with high-risk HER2-positive breast cancer after surgery or adjuvant therapy, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared with trastuzumab alone, according to final trial results KATHERINE phase III clinical trial conducted by scientists from the University of Pittsburgh and UPMC […]